Protein concentration profiles simulated by the model. Panel (A) includes the inputs from the Chen et al.  model used to drive our network (Clb5 and Cdc20), scaled from arbitrary units to molecules/cell. Included are the behaviours of various protein factors within our model. Additional factors, replication complexes (RCs) as well as the FORK species are shown in panel (B). The transient RC species (RC2, RC4 and RC5) are shown in panel (C).