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Figure 1 | BMC Systems Biology

Figure 1

From: Rational drug repositioning guided by an integrated pharmacological network of protein, disease and drug

Figure 1

Overview of PharmDB. Nine different databases were integrated using standard IDs (Entrez Gene ID for protein, PubChem CID for drug and MeSH Descriptor ID for disease) to construct PharmDB. The integrated network was analyzed using the shared neighborhood scoring algorithm, providing a predictive capacity for PharmDB to suggest functional relationships between diseases, proteins, and rugs. These data are provided through a web browser, phExplorer (network visualization software) and web service (http://www.i-pharm.org/, http://biomart.i-pharm.org/).

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