Phosphorylation duration and amplitude of the output MK-PP in the four MAPK cascades subjected to a range of input signals in M1K2- M4K2. (A)-(H) Input signal of various strengths but of fixed duration (600 s) was applied and amplitude and duration of MK-PP in response to each of the applied signal was plotted. In the plots, x axis represents the signal strength and the two y axis represents signal amplitude and duration corresponding to a signal strength. As shown in the plots, blue colour represents the amplitude and green colour represents the duration of the output signal (MK-PP). Results for both USEQ and PSEQ conditions are shown for M1K2 - M4K2 with respective labelling.