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Figure 9 | BMC Systems Biology

Figure 9

From: Different designs of kinase-phosphatase interactions and phosphatase sequestration shapes the robustness and signal flow in the MAPK cascade

Figure 9

Phosphorylation duration and amplitude of the output MK-PP in the four MAPK cascades subjected to a range of input signals in M1K1- M4K1. (A)-(H)Input signal of various strengths but of fixed duration (600 s) was applied and amplitude and duration of MK-PP in response to each of the applied signal was plotted. In the plots, x axis represents the signal strength and the two y axis represents signal amplitude and duration for the given signal strength. As shown in the plots, blue colour represents the amplitude and green colour represents the duration of the output signal (MK-PP). Results for both USEQ and PSEQ conditions are shown for M1K1 - M4K1 with respective labelling.

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