Figure 2From: An investigation of spatial signal transduction in cellular networksResponse of the coherent feedforward module. An example of the (A) gradient signal input and the (B) localized signal input used in the analysis is shown (as a function of the domain postition). In this and other simulations the graded signal has a cosine variation and is of the form S = a + bcosθ. The localized signal is of the form a + Aexp(x−x o )/α. The module is subjected to a (C) gradient signal input and a (D) localized signal input and the response is shown for either when none of the elements are diffusible (solid line with circles) or when the X pathway (solid line) or the Y pathway (dashed line) is highly diffusible. The scenario where pathway X is stronger than pathway Y is shown here. In each case the response qualitatively mirrors the signal. When X diffuses, the spatial variation of the response is weaker than when Y diffuses. In both these cases, the response element exhibits weaker spatial variation when compared to the non-diffusible case.Back to article page