Skip to main content
Figure 8 | BMC Systems Biology

Figure 8

From: An investigation of spatial signal transduction in cellular networks

Figure 8

Response of the monostable switch module. Xis shown in response to a smooth gradient signal (of the form a + bsinθ, with a maximum at θ = Π/2 ) for a (A) non-diffusible and (C) highly diffusible case and a localized signal input (of the form of a square pulse) for a (B) non-diffusible and (D) highly diffusible case. (A) The concentration profile of Xis broader near the maxima and minima of the signal and it exhibits a spatial switch-like behaviour. (B) The spatial profile of Xis qualitatively similar to the signal. (C,D) Xis shown here for when X is highly diffusible (solid line) and non-diffusible (dashed line). (C) In response to the gradient signal, the spatial profile of Xincreases sharply in the region where the signal crosses a threshold value. Thus the diffusion of X leads to an enhancement of the spatial switch response. (D) For the localized signal, the spatial profile of Xshows greater contrast when X is highly diffusible.

Back to article page