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Table 6 Number of essential proteins identified by ION and seven other existing centrality methods based on protein data from E. coli

From: Iteration method for predicting essential proteins based on orthology and protein-protein interaction networks

K

DC

IC

EC

SC

BC

CC

NC

ION

1%(27)

8

7

2

2

9

7

3

8

5%(136)

38

36

34

34

40

36

35

51

10%(273)

69

68

60

60

65

67

60

85

15%(409)

94

95

93

93

84

92

82

104

20%(545)

116

112

110

110

103

113

94

122

25%(682)

129

127

124

124

120

130

118

153

  1. This table shows the comparison of the number of essential proteins identified by ION and seven other existing centrality methods (DC, BC, CC, SC, EC, IC and NC) based on protein data from E. coli. Since the total number of ranked proteins in E. coli is 2727. The number of proteins ranked in top 1% is about 27(=2727*1%). The digits in brackets denote the number of proteins ranked in each top percentage.
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