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Figure 4 | BMC Systems Biology

Figure 4

From: Absorbing phenomena and escaping time for Muller's ratchet in adaptive landscape

Figure 4

The approximated single click time decreases with mutation rates increasing in the regime μ ∊ (2 N /4 N ( N - 1), 1) and σ∈ ( ( 2 + 2 μ - 10 N μ + 4 N 2 μ + 2 N μ 2 + 4 ( 1 - μ ) N ( N - 1 ) ( ( 2 N - 1 ) μ - 1 ) ) / ( μ - 2 N + 1 ) 2 , ( 2 N μ - 1 ) / ( 2 N μ - μ ) ) denoted by I iv). Assume N=100, blue, black and dashed lines, corresponding high mutation rates regime, represent μ=210/(400*99), μ=500/(400*99) and μ=1000/(400*99) respectively. Red and green lines, corresponding low mutation rates regime, represent μ=210/(400*99) and μ=500/(400*99) respectively. The approximated single click time increases with mutation rates increasing in the regime μ (1/(2N-1),1) and σ ((2Nμ-1)/(2Nμ-μ),1) denoted by I iii). Green dotline represents this case.

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