Methods comparison via volcano like plots. Comparison of our LPFS method with existing methods regarding to the identified biomarkers. All the 400 metabolites are plotted into a two dimensional plane. The selected biomarkers are highlighted in red. The x-axis denotes the difference of means and the y-axis denotes the standard derivation. Good biomakers should locate either in the left bottom corner or in the right bottom corner. a) volcano like plot of t-test method. The top 10 features are in red. b) volcano like plot of fold change method. The top 10 features are in red. c) volcano like plot of SMLR method. d) volcano like plot of SVM-RFE method. e) volcano like plot of our LPFS method.