BMC Systems Biology

Table 2 TFs identified by network screening in terms of coverage.

From: A computational procedure for identifying master regulator candidates: a case study on diabetes progression in Goto-Kakizaki rats

4w				8w_12w				16w_20w
GK		WKY		GK		WKY		GK		WKY
TF	No. of regulated genes	TF	No. of regulated genes	TF	No. of regulated genes	TF	No. of regulated genes	TF	No. of regulated genes	TF	No. of regulated genes
SP1	10	SP1	19	SP1	39	SP1	18	SP1	12	SP1	5
		SP3	8	SP3	11	HNF4A	6	SP3	3	FOXO3	3
		TP53	4	TP53	11	FOXO3	4
				EGR1	6
				NRF1	6
				TCFAP2A	5

TFs found in both GK and WKY are indicated by bold letters.

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ISSN: 1752-0509

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