The preservation of bidirectional promoter architecture in eukaryotes: what is the driving force?

Xu, Chao; Chen, Jiajia; Shen, Bairong

doi:10.1186/1752-0509-6-S1-S21

BMC Systems Biology

Table 2 Enriched KEGG pathways of bidirectional genes in eight different species.

From: The preservation of bidirectional promoter architecture in eukaryotes: what is the driving force?

Pathway	human	mouse	rat	cow	chicken	fruit fly	C.elegans	yeast	Count
Spliceosome	hsa03040	mmu03040	rno03040	bta03040	gga03040	dre03040	cel03040	sce03040	8
RNA degradation	hsa03018	mmu03018	rno03020	bta03018		dre03018	cel03018	sce03018	7
Nucleotide excision repair	hsa03420	mmu03420	rno03420		gga03420	dre03420	cel03420	sce03420	7
RNA polymerase	hsa03020	mmu03020		bta03020		dre03020	cel03030	sce03020	6
Non-homologous end-joining	hsa03450		rno03450	bta03450	gga03450	dre03450	cel03450		6
Oxidative phosphorylation	hsa00190	mmu00190	rno00190	bta00190	gga00190		cel00190		6
Pyrimidine metabolism	hsa00240	mmu00240				dre00240	cel00240	sce00240	5
Ribosome	hsa03010			bta03010		dre03010	cel03010	sce03010	5
Base excision repair	hsa03410			bta03410	gga03410	dre03410		sce03410	5
Purine metabolism		mmu00230				dre00230	cel00230	sce00230	4
DNA replication	hsa03030	mmu03030				dre03030		sce03030	4
Proteasome					gga03050	dre03050	cel03050	sce03050	4
Mismatch repair	hsa03430					dre03430	cel03430	sce03430	4
Homologous recombination	hsa03440	mmu03440				dre03440	cel03440		4
Aminoacyl-tRNA biosynthesis	hsa00970		rno00970		gga00970		cel00970		4
N-Glycan biosynthesis		mmu00510	rno00510				cel00510		3
Cell cycle	hsa04110	mmu04110	rno04110						3
Peroxisome	hsa04146	mmu04146	rno04146						3
Systemic lupus erythematosus	hsa05322	mmu05322		bta05322					3
O-Mannosyl glycan biosynthesis		mmu00514			gga00514			sce00514	3
Folate biosynthesis						dre00790	cel00790	sce00970	3
Metabolic pathways(Global Pathway)	hsa01100						cel01100	sce01100	3
Protein export						dre03060	cel03060	sce03060	3
Basal transcription factors						dre03022		sce03022	2
SNARE interactions in vesicular transport						dre04130		sce04130	2
Parkinson's disease	hsa05012			bta05012					2
Citrate cycle (TCA cycle)			rno00020				cel00020		2

The first three letters represent the abbreviation of each organism and the following numbers mean the accession number of the pathway in KEGG. The COUNT is the number of species which is enriched with the pathway. The pathways which only enriched in one organism were excluded.

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ISSN: 1752-0509

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