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Figure 4 | BMC Systems Biology

Figure 4

From: Natural selection drives rapid evolution of mouse embryonic heart enhancers

Figure 4

Properties of heart enhancers. Heart enhancers include more specific enhancers (A) and enhancers adjacent to highly expressed genes (B). (A) The numbers in boxes represent the number of enhancers in a group. (B) The values of upper quartile, median, and lower quartile are indicated in each box, whereas the bars outside the box indicate semi-quartile ranges. Pairwise comparisons with significantly different expression levels of the adjacent gene are connected with gray lines (*0.01<P0.05 and ***P0.001 by (A) × 2 test or (B) Mann-Whitney U test). FB, forebrain; MB, midbrain; LB, limb; HT, heart.

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