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Table 4 Non-small-cell lung cancer data set analysis

From: Statistical aspects of omics data analysis using the random compound covariate

Method

Pathway

Coef

RR

p-value

Overall p-value

SRC B

NOD

0.033

1.0013

0.59

0.236

 

P53

0.037

1.0044

0.67

 

SRC W

NOD

0.016

1.0063

0.37

0.358

 

P53

0.001

1.0002

0.99

 

SC B

NOD

0.077

1.08

0.36

0.432

 

P53

0.015

1.01

0.90

 

SC W

NOD

0.034

1.03

0.24

0.432

 

P53

-0.01

0.99

0.74

 

DC B

NOD

0.072

1.07

0.37

2.29 × 10-6

 

P53

0.314

1.37

0.003

 

DC W

NOD

0.019

1.02

0.21

1.85 × 10-5

 

P53

0.055

1.06

0.006

 
  1. To evaluate the 90 gene expression profiling from National Center for Biotechnology Information Gene Expression Omnibus (GSE14814). The first signaling pathway is the p53 pathway. The other pathway is the NOD-like receptor signaling pathway.