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Table 2 Description of additional gene sets.

From: Integrative pathway analysis of genome-wide association studies and gene expression data in prostate cancer

Gene set Size Description
PGDB 129 Genes extracted from the PGDB database [28]
GWAS_Top30 30 Top 30 genes with the smallest association P-values in GWAS.
GWAS_TopP-4 69 Top 69 genes with association P < 10-4 in GWAS
DEG_LR_1 165 DEGs in gene expression data with FDR < 0.05, and absolute log2 ratio (LR) > 1
DEG_LR_1.5 130 DEGs in gene expression data with FDR < 0.05, and absolute LR > 1.5
DEG_LR_2 13 DEGs in gene expression data with FDR < 0.05, and absolute LR > 2
  1. DEG: differentially expressed gene (DEG). FDR value was based on t-test. More details of gene sets are provided in the text.