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Table 4 Significant pathways (FDR < 0.01) detected by the Plink set-based test.

From: Integrative pathway analysis of genome-wide association studies and gene expression data in prostate cancer

Pathway (KEGG ID) P FDR
Jak-STAT signaling pathway (hsa04630)* 0.001 0.043
Chronic myeloid leukemia (hsa05220) 0.001 0.043
Small cell lung cancer (hsa05222) 0.001 0.043
TGF-beta signaling pathway (hsa04350) 0.002 0.043
Endometrial cancer (hsa05213) 0.002 0.043
Thyroid cancer (hsa05216)* 0.002 0.043
Bladder cancer (hsa05219) 0.002 0.043
Acute myeloid leukemia (hsa05221) 0.002 0.043
Cell cycle (hsa04110) 0.003 0.043
Wnt signaling pathway (hsa04310) 0.003 0.043
Fc gamma R-mediated phagocytosis (hsa04666) 0.003 0.043
Regulation of actin cytoskeleton (hsa04810) 0.003 0.043
Colorectal cancer (hsa05210) 0.003 0.043
The PGDB gene set 0.004 0.053
ErbB signaling pathway (hsa04012) 0.008 0.099
  1. *Overlap with SRT.
  2. Overlap with GSEA.