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Table 6 Significant pathways in prostate cancer microarray gene expression data detected by the GSEA method.

From: Integrative pathway analysis of genome-wide association studies and gene expression data in prostate cancer

Pathway (KEGG ID) ES NES P FDR
Fc gamma R-mediated phagocytosis (hsa04666)* 0.645 1.809 < 0.001 0.131
Focal adhesion (hsa04510) 0.482 1.658 0.004 0.176
Dilated cardiomyopathy (hsa05414) 0.672 1.905 0.004 0.101
Hypertrophic cardiomyopathy (HCM) (hsa05410) 0.619 1.740 0.009 0.122
Regulation of actin cytoskeleton (hsa04810)* 0.464 1.714 0.009 0.128
Leukocyte transendothelial migration (hsa04670) 0.594 1.760 0.011 0.163
Arrhythmogenic right ventricular cardiomyopathy (ARVC) (hsa05412) 0.663 1.760 0.012 0.123
  1. ES: enrichment score. NES: normalized enrichment score.
  2. *Overlap with the Plink set-based results.
  3. Overlap with the GenGen results.