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Table 1 SNP pairs detected when testing among SNPs located in the same genes.

From: Gene, pathway and network frameworks to identify epistatic interactions of single nucleotide polymorphisms derived from GWAS data

SNP1

p-value (SNP1)

SNP2

p-value (SNP2)

p-value (interaction)

Distance

correlation

Genes

rs1994385

3.7 × 10-1

rs2389493

3.3 × 10-5

1.3 × 10-8

8 k

0.63

NDST3

rs2389493

3.3 × 10-5

rs6534079

3.0 × 10-1

1.6 × 10-8

17 k

0.63

 

rs6421008

4.8 × 10-1

rs7827545

1.4 × 10-3

1.5 × 10-11

54 k

0.07

ZFAT

rs356127

9.2 × 10-1

rs2406898

1.5 × 10-5

9.4 × 10-9

63 k

0.37

 

rs7853126

6.5 × 10-1

rs2406898

1.5 × 10-5

1.2 × 10-8

129 k

0.37

C9orf3

rs2584803

8.3 × 10-1

rs2406898

1.5 × 10-5

1.2 × 10-8

73 k

0.37

 

rs17097262

3.4 × 10-1

rs7154773

5.7 × 10-5

1.7 × 10-10

10 k

0.04

 

rs7154773

5.7 × 10-5

rs10130695

2.3 × 10-1

3.5 × 10-10

6.9 k

0.04

PPM1A

rs12323784

2.0 × 10-1

rs7154773

5.7 × 10-5

6.1 × 10-10

338 bp

0.05

 
  1. Correlation: correlation coefficient between two SNPs