Table 3 Top-ranking T2D risk genes ordered by their r mod scores in the T2D risk gene protein interaction network.
From: Genome-wide meta-analysis of genetic susceptible genes for Type 2 Diabetes
Rank by r mod Score | Gene | r mod Score | r p Score | Original Rank by r p Score |
|---|---|---|---|---|
1 | ENPP1 | 430 | 74.3 | 3 |
2 | ESR1 | 142 | 77.7 | 2 |
3 | IL6 | 137 | 67.0 | 4 |
4 | IL10 | 132 | 60.2 | 5 |
5 | GCK | 119 | 46.2 | 11 |
6 | HNF4A | 118 | 4.72 | ≫ 13 |
7 | PIK3R1 | 114 | - | 1 |
8 | TNF | 110 | 3.75 | ≫ 13 |
9 | IRS2 | 110 | - | > 13 |
10 | HNF1A | 105 | - | > 13 |
11 | PPARG | 82.9 | 4.27 | ≫ 13 |
12 | PTPN1 | 69.8 | 3.69 | ≫ 13 |
13 | IL6R | 61.0 | - | > 13 |