Table 4 Enriched pathways identified in the T2D risk genes.
From: Genome-wide meta-analysis of genetic susceptible genes for Type 2 Diabetes
Term | Count | % | P-value |
|---|---|---|---|
Adipocytokine signalling pathway | 15 | 7.01 | 6.21E-11 |
Type II diabetes mellitus | 12 | 5.61 | 2.18E-09 |
Insulin signalling pathway | 17 | 7.94 | 1.60E-08 |
Maturity onset diabetes of the young | 8 | 3.74 | 5.63E-07 |
PPAR signalling pathway | 9 | 4.21 | 9.11E-05 |
Calcium signalling pathway | 10 | 4.67 | 1.20E-02 |
Renal cell carcinoma | 6 | 2.80 | 1.60E-02 |
Hypertrophic cardiomyopathy (HCM) | 6 | 2.80 | 3.38E-02 |
Aldosterone-regulated sodium reabsorption | 4 | 1.87 | 5.55E-02 |
VEGF signalling pathway | 5 | 2.34 | 7.43E-02 |
Adherens junction | 5 | 2.34 | 8.02E-02 |
Pathways in cancer | 12 | 5.61 | 8.68E-02 |