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Table 2 The top 10 instances obtained from gene modularization comparison method and distance comparison method in hypoxia case

From: A cross-species analysis method to analyze animal models' similarity to human's disease state

A.

cMap ID

Molecule

GO counts

B.

cMap ID

Molecule

 

595

resveratrol

25+

 

573

deferoxamine [INN]

 

1015

genistein

22+

 

1068

thioridazine [INN]

 

970

5230742

21+

 

418

haloperidol [INN]

 

1068

thioridazine [INN]

20+

 

921

sirolimus [INN]

 

573

deferoxamine [INN]

20+

 

1080

sirolimus [INN]

 

1004

trifluoperazine [INN]

19+

 

906

calmidazolium

 

991

tretinoin [INN]

18-

 

904

5109870

 

871

ionomycin

18+

 

1075

fluphenazine [INN]

 

921

sirolimus [INN]

17+

 

977

wortmannin

 

444

clofibrate [INN]

17-

 

417

thioridazine [INN]

  1. The top 10 instances sharing the largest number of significantly affected GOMs with bone marrow cells form hypoxia model are listed in A and the top 10 instances resulted from distance comparison method are listed in B.
  2. Detailed parameter settings: GO mode: BP; P-value: < 0.05.