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Table 3 The top 10 instances obtained from gene modularization comparison method and distance comparison method in Diabetes case

From: A cross-species analysis method to analyze animal models' similarity to human's disease state

A. cMap ID Molecule GO counts B. cMap ID Molecule
  1069 15-delta prostaglandin J2 63+   941 rottlerin
  887 celastrol 54+   839 5224221
  893 pararosaniline 54+   1069 15-delta prostaglandin J2
  1011 15-delta prostaglandin J2 53+   978 pyrvinium
  839 5224221 53+   956 5224221
  956 5224221 51+   887 celastrol
  941 rottlerin 51+   893 pararosaniline
  1140 MG-132 46+   1140 MG-132
  1010 thioridazine [INN] 45+   1010 thioridazine [INN]
  976 5182598 44+   1011 15-delta prostaglandin J2
  1. The top 10 instances sharing the largest number of significantly affected GOMs with adipocyte tissue fed by metformin are listed in A and the top 10 instances resulted from distance comparison method are listed in B.
  2. Detailed parameter settings: GO mode: BP; P-value: < 0.05.