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Table 4 The top 10 instances obtained from gene modularization comparison method and distance comparison method in Alzheimer case

From: A cross-species analysis method to analyze animal models' similarity to human's disease state

A. cMap ID Molecule GO counts B. cMap ID Molecule
  415 nordihydroguaiaretic acid 25-   367 fulvestrant
  966 tretinoin [INN] 22-   447 tretinoin
  513 LY-294002 21-   3 metformin
  367 fulvestrant [INN] 20+   582 butein
  1048 alpha-estradiol 18-   419 chlorpromazine
  988 estradiol [INN] 15- 1+   942 prazosin
  953 monorden 16- 1+   970 5230742
  502 prazosin [INN] 17+   448 trichostatin A
  361 LY-294002 9- 8+   254 SC-58125
  866 ikarugamycin 16+   460 deferoxamine
  1. The top 10 instances sharing the largest number of significantly affected GOMs with Alzheimer hippocampus cells are listed in A and the top 10 instances resulted from distance comparison method are listed in B.
  2. For detailed parameter settings: GO mode: BP; P-value: < 0.05.