Hierarchical clustering for modules. Each rectangle represents a module and the number above is the module's index. Each color denotes a biological process according to the KEGG pathway classification and its area in one rectangle reflects the proportion of the corresponding biological process in this module. The biological processes named "other" are reactions that do not exist in any KEGG human pathway. The dotted lines classified the 28 modules into 8 clusters according to the hierarchical tree in this figure.