Table 2 Main function of each cluster and corresponding enrichment of CPP differential urine metabolites.
Cluster ID | Main Function | Modules included | Total metabolites | CPP differential urine metabolites | P-value |
|---|---|---|---|---|---|
1 | Lipid metabolism | 10,28,24,25,2,11 | 280 | 3 | 0.971 |
2 | Unknown | 21,20,12,19 | 170 | 1 | 0.986 |
3 | Largely unknown containing partial amino acid metabolism | 15,3,4,13 | 251 | 4 | 0.859 |
4 | Metabolism of Cofactors and Vitamins | 16,17 | 51 | 1 | 0.703 |
5 | Carbohydrate Metabolism | 6,1,8 | 165 | 4 | 0.541 |
6 | Xenobiotics Biodegradation and Metabolism | 27 | 33 | 0 | 1.000 |
7 | Nucleotide Metabolism | 5,23 | 152 | 7 | 0.053 |
8 | Amino Acid Metabolism | 9,18,7,26,14,22 | 284 | 12 | 0.019 |