Table 2 Performance comparison on Gavin_2006 with CYC-2008
From: Detection of protein complexes from affinity purification/mass spectrometry data
PPI networks | Gavin_2006 | ||||||
|---|---|---|---|---|---|---|---|
Evaluation Metric | MCL | MCODE | CFinder | COACH | CODEC-w0 | CODEC-w1 | Our method |
Sensitivity | 0.721 | 0.338 | 0.390 | 0.596 | 0.584 | 0.582 | 0.434 |
PPV | 0.296 | 0.342 | 0.365 | 0.120 | 0.511 | 0.546 | 0.747 |
Accuracy | 0.462 | 0.340 | 0.377 | 0.268 | 0.546 | 0.564 | 0.570 |
Complex-wise Homogeneity | 0.156 | 0.123 | 0.087 | 0.048 | 0.234 | 0.272 | 0.318 |
Cluster-wise Homogeneity | 0.875 | 0.748 | 0.613 | 0.030 | 0.086 | 0.107 | 0.848 |
Homogeneity | 0.369 | 0.303 | 0.231 | 0.038 | 0.141 | 0.171 | 0.519 |