Table 3 Performance comparison on Gavin_2006 with GO-CC
From: Detection of protein complexes from affinity purification/mass spectrometry data
PPI networks | Gavin_2006 | ||||||
|---|---|---|---|---|---|---|---|
Evaluation Metric | MCL | MCODE | CFinder | COACH | CODEC-w0 | CODEC-w1 | Our method |
Sensitivity | 0.655 | 0.333 | 0.358 | 0.549 | 0.524 | 0.529 | 0.420 |
PPV | 0.241 | 0.337 | 0.335 | 0.107 | 0.314 | 0.405 | 0.648 |
Accuracy | 0.397 | 0.335 | 0.346 | 0.242 | 0.406 | 0.463 | 0.522 |
Complex-wise Homogeneity | 0.164 | 0.140 | 0.087 | 0.050 | 0.249 | 0.288 | 0.350 |
Cluster-wise Homogeneity | 0.845 | 0.746 | 0.536 | 0.027 | 0.098 | 0.123 | 0.800 |
Homogeneity | 0.373 | 0.323 | 0.216 | 0.036 | 0.156 | 0.188 | 0.529 |