Table 5 Performance comparison on Krogan_2006 with GO-CC
From: Detection of protein complexes from affinity purification/mass spectrometry data
PPI networks | Krogan_2006 | ||||||
|---|---|---|---|---|---|---|---|
Evaluation Metric | MCL | MCODE | CFinder | COACH | CODEC-w0 | CODEC-w1 | Our method |
Sensitivity | 0.644 | 0.274 | 0.340 | 0.638 | 0.543 | 0.517 | 0.303 |
PPV | 0.102 | 0.126 | 0.354 | 0.060 | 0.350 | 0.361 | 0.443 |
Accuracy | 0.257 | 0.186 | 0.347 | 0.196 | 0.436 | 0.432 | 0.366 |
Complex-wise Homogeneity | 0.049 | 0.039 | 0.076 | 0.015 | 0.241 | 0.225 | 0.138 |
Cluster-wise Homogeneity | 0.450 | 0.469 | 0.511 | 0.002 | 0.026 | 0.046 | 0.729 |
Homogeneity | 0.149 | 0.136 | 0.197 | 0.006 | 0.079 | 0.102 | 0.317 |