Table 7 Specificity/sensitivity/F-measure results on the two testing PPI networks with CYC-2008 and GO-CC benchmark complexes on Gavin_2006
From: Detection of protein complexes from affinity purification/mass spectrometry data
| Â | MCL | MCODE | CFinder | COACH | CODEC-w0 | CODEC-w1 | Our method |
|---|---|---|---|---|---|---|---|
CYC_2008 | Â | Â | Â | Â | Â | Â | Â |
Specificity | 0.859 | 0.610 | 0.804 | 0.252 | 0.305 | 0.459 | 0.889 |
Sensitivity | 1.000 | 1.000 | 1.000 | 1.000 | 1.000 | 1.000 | 1.000 |
F-Measure | 0.924 | 0.758 | 0.891 | 0.403 | 0.468 | 0.630 | 0.941 |
GO_CC | Â | Â | Â | Â | Â | Â | Â |
Specificity | 0.836 | 0.585 | 0.761 | 0.197 | 0.385 | 0.533 | 0.839 |
Sensitivity | 0.939 | 0.456 | 0.897 | 0.963 | 0.993 | 0.994 | 0.963 |
F-Measure | 0.885 | 0.512 | 0.824 | 0.328 | 0.555 | 0.694 | 0.897 |