Table 2 Metabolic model performance in predicting antibacterial effects
From: Antibacterial mechanisms identified through structural systems pharmacology
Negative control | Positive controls | ||||||||
|---|---|---|---|---|---|---|---|---|---|
BGC | FCN | YTZ | TOP | H3P | |||||
No growth upon inhibition | - | AcpP | FabB | FolC | FolP | ThyA | Fabl | ||
Gmk | IspA | IspB | |||||||
MurA | MurE | PgsA | |||||||
PlsC | |||||||||
No effect upon inhibition | GalP | GlgY | Glk | FbaA | TolC | FolA | FolA | - | |
MglB | XylA | YlaD | |||||||