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Table 2 List of previous reports of individual miRNAs in biological processes or liver diseases of the liver and bile duct based on published literature (, as of 5/3/2012)

From: Integrative genomics identifies candidate microRNAs for pathogenesis of experimental biliary atresia

Name Relationship: liver Relationship: bile duct
miR-126-3p No report No report
miR-30b Inhibited TGF beta1-induced EMT, [24] downregulated after hepatectomy in rats [29] Upregulated in LPS-induced Activated NFκB in cholangiocytes [25]
miR-30c Required for hepatobiliary development [10] Required for hepatobiliary development, [10] upregulated after C.parvum infection [26]
miR-151-3p No report No report
miR-320 Downregulated in Huh7 cells after HCV infection [21] Downregulated in intrahepatic cholangiocarcinoma, involved in drug-triggered apoptosis [28]
miR-676 No report No report
miR-204 No report Downregulated in intrahepatic cholangiocarcinoma [28]
miR-193b Downregulated in HCC, [13] upregulated in a HCC cell line after transfection of HCV genome [20] No report
miR-365 No report No report
miR-133a No report No report
miR-200b Downregulated in HCC, [18, 19] upregulated in NAFLD and NASH [22, 23] Upregulated in cholangiocarcinoma cell lines [27]
miR-133b No report No report
miR-200a Downregulated in HCC [15] and inhibited the proliferation and migration of HCC cells, [17] upregulated in NAFLD [23] No report
miR-195 Downregulated in HCC, [15] suppressed growth of HCC, [14] sensitized HCC to 5-fluorouracil, [16] inhibited proliferation of HSC [30] No report
  1. TGF: transforming growth factor, LPS: lipopolysaccharide, HCC: hepatocellular carcinoma, HCV: Hepatitis C virus, EMT: epithelial-to-mesenchymal transition, NAFLD: nonalcoholic fatty liver disease, NASH: nonalcoholic steatohepatitis, HSC: hepatic stellate cells.