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Table 1 Description of UMs

From: Solving gap metabolites and blocked reactions in genome-scale models: application to the metabolic network of Blattabacterium cuenoti

UM Related to subsystem No. reactions No. metabolites RNP RNC
1 Menaquinol Biosynthesis 23 21 Mev, 2ombzl 2ommbl
2 Nucleotide Salvage Pathway 22 15 - Hxan, xan, r1p, 2dr1p, thym, ura
3 Pyridoxal 5-phosphate Biosynthesis 7 6 - 4hthr
4 Lipopolysaccharide Biosynthesis 4 4 - u3hga
5 Siroheme Biosynthesis 4 4 - uppg3
6 Arginine and Proline Metabolism 2 2 - 1pyr5c
7 Transport, Extracellular (Fe2+) 2 2 - Fe2+
8 Transport, Extracellular (K+) 2 2 - K+
9 Superoxide Dismutase 1 1 O2 -
10 Acyl-Carrier Protein Synthase 1 1 apoACP -
  Total 68 58 8 4
  1. UM identified in B. cuenoti iCG238 GSM. Metabolite abbreviations: Mev (mevalonate), 2ombzl (2-Octaprenyl-6-methoxy-1,4-benzoquinol), 2ommbl (2-Octaprenyl-3-methyl-6-methoxy-1,4-benzoquinol), hxan (Hypoxanthine), xan (Xanthine), r1p (Ribose-1-phosphate), 2dr1p (2-deoxy-D-Ribose-1-phosphate, thym (Thymine), ura (Uracil) 1pyr5c (1-Pyrroline-5-carboxylate), 4hthr (4-Hydroxy-L-threonine), u3hga (UDP-3-O-(3-hydroxytetradecanoyl)-D-glucosamine), uppg3 (Uroporphyrinogen), apoACP (apoprotein [acyl carrier protein]). The relation between an UM and a subsystem was established according to the most frequent subsystem associated to the reactions of the UM.