Compartment | Meaning | Biological equivalents |
---|---|---|
S | hematopoietic stem cells | hematopoietic stem cells |
CG | granulopoietic progenitor cells | CFU-GM (colony forming units of granulocytes and macrophages) |
PGB | proliferating granulopoietic precursor cells | myeloblasts, promyelocytes, precursor myelocytes |
MGB | maturing granulopoietic precursor cells | metamyelocytes (G4), banded (G5) and segmented (G6) granulocytes |
GRA | granulocytes | granulocytes in circulation |
G | CG + PGB + MGB | total granulopoietic cells in bone marrow |
G-CSF | G-CSF (granulocyte colony-stimulating factor) | cytokine of granulopoiesis |
GM-CSF | GM-CSF (granulocyte, macrophage colony-stimulating factor) | cytokine of granulopoiesis |
CX | Chemotherapy | (damaging effect of) chemotherapy |