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Table 4 Parameter of the stem cell compartment in the hybrid model

From: Merging concepts - coupling an agent-based model of hematopoietic stem cells with an ODE model of granulopoiesis

Time step Δt 1 h
Differentiation coefficient d 1.10252
Regeneration coefficient r 1.05001
Threshold to differentiated cells a min 0.002
Maximum stem cell affinity a max 1.0
Cycle time τc 49 h
S/G2/M-phase τS 17 h
Transition Characteristics
Ω → Α fΑ(0) 0.5
fΑ( ÑΑ /2) 0.45
fΑ( ÑΑ ) 0.05
fΑ(∞) 0.0
Ñ Α 105
Α → Ω fΩ(0) 0.5
fΩ( ÑΩ /2) 0.3
fΩ( ÑΩ) 0.1
fΩ(∞) 0.0
Ñ Ω 105