Ovarian cancer gene signature. Gene signature constructed from the expression values for each of genes given in Table 2, by substracting the sum of the down-regulated gene expression values from the sum of the up-regulated gene expression values. A. Individual scores for each of the normal and cancer patients. B. Mean signature values +/- (SEM) for the normal and cancer patients. Welch two sample t-test (t = -14.69, df = 8.45, p=2.621E-07).