Skip to main content

Table 7 Pathways regulated by miRNA-TF synergistic regulatory network

From: Functional analysis of microRNA and transcription factor synergistic regulatory network based on identifying regulatory motifs in non-small cell lung cancer

Pathway name Ranka In motifsb
p53 pathway 1 8
Direct p53 effectors 2 8
Regulation of Telomerase 3 7
Hypoxia and oxygen homeostasis regulation of HIF-1-alpha 4 8
Arf6 signaling events 5 8
Cell Cycle, Mitotic 6 7
S Phase 7 6
Synthesis of DNA 8 7
DNA Replication 9 6
Regulation of DNA replication 13 5
G1/S Transition 10 6
IGF1 pathway 11 6
Orc1 removal from chromatin 12 5
Switching of origins to a post-reflective state 14 5
Removal of licensing factors from origins 15 5
Signaling events regulated by Ret tyrosine kinase 16 4
EphrinA-EPHA pathway 17 3
E-cadherin signaling events 18 7
FOXA transcription factor networks 19 6
E2F transcription factor network 20 7
Neurotrophic factor-mediated Trk receptor signaling 21 9
Canonical Wnt signaling pathway 22 7
  1. aRank: is the rank number calculated using the formula (2.7.1) based on the number of occurrences of the pathways among all the assigned pathways.
  2. bIn motifs: is how many motif subnetworks were assigned the corresponding pathways.