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Figure 1 | BMC Systems Biology

Figure 1

From: (Im)Perfect robustness and adaptation of metabolic networks subject to metabolic and gene-expression regulation: marrying control engineering with metabolic control analysis

Figure 1

The end-product module with gene-expression and metabolic regulation. x1, x2, …, x n represent the concentrations of metabolites in the pathway; E1, E2, … are the concentrations of enzymes catalysing each reaction. For illustration, only the enzyme of the first reaction (E1) is assumed negatively regulated via both metabolic (allosteric) effect and gene-expression regulation through the end product x n .

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BMC Systems Biology

ISSN: 1752-0509

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