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Figure 10 | BMC Systems Biology

Figure 10

From: (Im)Perfect robustness and adaptation of metabolic networks subject to metabolic and gene-expression regulation: marrying control engineering with metabolic control analysis

Figure 10

A linear end-product pathway with gene-expression and metabolic regulation. The metabolites are denoted by x i , mRNA by mR and enzymes by E. S and P are the external metabolites. Metabolite x3 inhibits the rate of enzyme 1 through metabolic regulation and the synthesis of enzyme 1, 2 and 3 through gene-expression regulation. Enzymes 1, 2 and 3 are encoded on the same operon.

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