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Figure 15 | BMC Systems Biology

Figure 15

From: (Im)Perfect robustness and adaptation of metabolic networks subject to metabolic and gene-expression regulation: marrying control engineering with metabolic control analysis

Figure 15

Illustration of the hierarchical supply–demand structure of the leucine biosynthetic pathway. a1 and b1 denote the synthesis and degradation of enzyme Leu1 (E1); a2 and b2 denote the synthesis and degradation of enzyme Leu2 (E2). s and d represent the supply and demand modules as shown in Figure 14.

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