Figure 2
Pathways for L-Alanine degradation to Pyruvate. A Canonical pathway extracted from [53]; B, C, D Alternative pathways calculated using iCFP. Metabolites: 3MOB, 3-Methyl-2-oxobutanoate; D-Ala, D-Alanine; L-Val, L-Valine; NH4, Ammonium; Pydx5P, Pyridoxal 5′-phosphate; PyAm5P, Pyridoxamine 5′-phosphate. Reactions: ALAR, alanine racemase; ALATA_D2, D-alanine transaminase; ALATA_L2, alanine transaminase; DAAD, D-Amino acid dehydrogenase; VPAMT, Valine-pyruvate aminotransferase. Highly/over expressed reactions are represented by solid lines, Medium expressed/invariant reactions by dashed lines and Lowly/down expressed reactions by dotted lines.