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Figure 4 | BMC Systems Biology

Figure 4

From: Integrating gene and protein expression data with genome-scale metabolic networks to infer functional pathways

Figure 4

A, Glu5sA is consumed to produce L-Pro; B, Glu5sA is consumed to produce L-Glu. Highly/over expressed reactions are represented by solid lines, Medium expressed/invariant reactions by dashed lines and Lowly/down expressed reactions by dotted lines. Metabolites: 1Pyr5c, 1-Pyrroline-5-carboxylate; Ac, Acetate; AcCoA, Acetyl-CoA; AcG5P, N-Acetyl-L-glutamyl 5-phosphate; AcG5sA, N-Acetyl-L-glutamate 5-semialdehyde; AcGlu, N-Acetyl-L-glutamate; Glu5sA, L-Glutamate 5-semialdehyde; L-Glu, L-Glutamate; L-Pro, L-Proline. Reactions: ACGK, acetylglutamate kinase; ACGS, N-acetylglutamate synthase; AGPR, N-acetyl-g-glutamyl-phosphate reductase; G5SADs, L-glutamate 5-semialdehyde dehydratase (spontaneous); NACODA, N-acetylornithine deacetylase; P5CD, 1-pyrroline-5-carboxylate dehydrogenase; P5CR, pyrroline-5-carboxylate reductase.

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