Table 2 Common DNA methylated genes across stages
From: Systems biology approach to stage-wise characterization of epigenetic genes in lung adenocarcinoma
Stages | DNA methylated genes | |
|---|---|---|
Number | List of genes | |
Common DNA methylated genes across the three stages | 34 | AJAP1, ATP8A2, CCDC140, CNTP2, CYYR1, EVX1, FERD3L, FOXG1, GRIK3, GRM6, HAND2, HOXA9, HOXB4, HOXD4, HOXD9, HOXD12, INPP5B, OTX2, KRTAP8-1, MMP26, PHOX2A, PLEKHA6, POU4F2, PRAC, PRKCB, PTGDR, REG3A, SIX6, SLC6A2, SPAG6, TBX20, TLX3, TMEM130, ZNF560 |
Common DNA methylated genes across Stage I & II | 12 | ADCY4, BHMT, C12orf34, CDO1, LVRN, LY96, MSC, PCDHGA12, POU3F3, ZNF154, ZNF577, IHH |
Common DNA methylated genes across Stage II & III | 30 | BARHL2, C10orf81, CCDC140, DEFB119, DIO3, FAM135B, FAM83A, GRIK2, HOXA4, HOXD10, HS3ST2, KCNS2, KRTAP15-1, LEP, LHX1, LYPD5, MAGEB6, NEUROG1, NKX6-2, OR5I1, SERPINB5, SPHKAP, TAL1, TBX4, TBX5, TCN1, TMEM132D, VSX1, ZNF454, IGKV7-3 |
Common hypermethylated genes across Stage I and Stage III | 42 | AJAP1, ATP8A2, CCDC140, CNTP2, CYYR1, EVX1, FERD3L, FOXG1, FOXI2, GALR1, GAS7, GRIK2, GRM6, HAND2, HLA-G, HOXA7, HOXA9, HOXB4, HOXD4, HOXD8, HOXD9, HOXD12, INPP5B, NID2, NPY, OTX2, PAX7, PHOX2A, PLEKHA6, POU4F2, PRAC, PRKCB, PTGDR, SIX6, SLC6A2, SOX17, SPAG6, TBX20, TLX3, TMEM130, VIPR2, ZNF560 |
Common hypomethylated genes across Stage I and Stage III | 4 | CORO6, MMP26, REG3A, KRTAP8-1 |