Figure 2From: A mathematical model of the unfolded protein stress response reveals the decision mechanism for recovery, adaptation and apoptosisThe generic receptor activation module for the activation dynamics of IRE1 α , PERK and ATF6. The receptor is shown with the symbol “R” with a cytoplasmic kinetic domain, and a luminal BiP-binding domain. Upon activation, the receptor oligomerises and autophosphorylates its cytoplasmic domain.Back to article page