Figure 5

The level of total BiP (BiPT) with increasing total UFP (UFPT) predicted by the IRE1 α module. The black solid curve indicates the increase in the level of BiP when there is no external regulation (for the reference model see Additional file 1: Text 1.2). The dashed curve indicates the deviation from this when XBP1 mRNA is induced externally (extXBP), and the dotted curve indicates the change when the BiP mRNA is induced externally (extBiP) to the same degree.