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Table 3 Estimated NAD/NADH ratio under different cultivation conditions

From: Glucose-methanol co-utilization in Pichia pastoris studied by metabolomics and instationary 13C flux analysis

 

pH (intracellular)

Substrate

7.0

7.2

7.5

Methanol-glucose

1906

1287

697

Glucosea

233

101

28

  1. aData taken from [53].
  2. Reported are the minimal NAD+/NADH ratios (NAD+/NADHmin), that fulfill the thermodynamic constraints (reaction directionality) at the measured and assumed concentrations (see Results section on Metabolome Analysis) for different intracellular pH.
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BMC Systems Biology

ISSN: 1752-0509

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