Annotated influence network. Influence network of the cell cycle G1/S transition generated by BIOCHAM. Colors represent differential expression obtained from transcriptomic data compared to normal tissue. Color intensities are proportional to the t-test statistic values (red values indicate positive values corresponding to an activation, green values indicate negative values corresponding to an inhibition). The three grey nodes are markers for the different cell cycle phases: G1 (pRB_star), S (CDK2/Cyclin E1 complex phosphorylated), M (CDC2/Cyclin E1 complex phosphorylated.