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Table 1 Comparison of BiNoM functionalities with other software tools

From: BiNoM 2.0, a Cytoscape plugin for accessing and analyzing pathways using standard systems biology formats

Function

BiNoM

CellDesigner

BioPAX2SBML

SyBiL

SBFC

Biographer

CySBML

ShortestPath

Glay

MCode

Moduland

ClusterMaker

NeMo

Standalone application

∘

•

•

•

•

•

∘

∘

∘

∘

∘

∘

∘

Cytoscape plugin

•

∘

∘

∘

∘

∘

•

•

•

•

•

•

•

BioPAX import

•

•

•

•

•

∘

∘

∘

∘

∘

∘

∘

∘

BioPAX visualization

•

•

∘

•

∘

∘

∘

∘

∘

∘

∘

∘

∘

BioPAX properties editor

•

∘

∘

∘

∘

∘

∘

∘

∘

∘

∘

∘

∘

BioPAX queries

•

∘

∘

∘

∘

∘

∘

∘

∘

∘

∘

∘

∘

BioPAX export

•

∘

∘

•

•

∘

∘

∘

∘

∘

∘

∘

∘

SBML import

•

•

∘

•

•

•

•

∘

∘

∘

∘

∘

∘

SBML visualization

•

•

∘

•

∘

•

•

∘

∘

∘

∘

∘

∘

SBML validation

∘

∘

∘

∘

•

∘

•

∘

∘

∘

∘

∘

∘

SBML layout and

             

qualitative support

∘

∘

•

∘

∘

∘

•

∘

∘

∘

∘

∘

∘

CellDesigner import,

             

visualization and export

•

•

∘

∘

∘

∘

∘

∘

∘

∘

∘

∘

∘

CSML import

•

∘

∘

∘

∘

∘

∘

∘

∘

∘

∘

∘

∘

CSML visualization

•

∘

∘

∘

∘

∘

∘

∘

∘

∘

∘

∘

∘

Cytoscape extra

             

utilities

•

∘

∘

∘

∘

∘

∘

∘

∘

∘

∘

∘

∘

Get connected

             

network components

•

∘

∘

∘

∘

∘

∘

∘

∘

•

∘

•

•

Semantic clustering

•

∘

∘

∘

∘

∘

∘

∘

∘

∘

∘

∘

∘

Community structure

             

clustering

∘

∘

∘

∘

∘

∘

∘

∘

•

∘

∘

∘

∘

Hierarchical modules

             

clustering

∘

∘

∘

∘

∘

∘

∘

∘

∘

∘

•

∘

∘

Multiple standard

             

clustering methods

∘

∘

∘

∘

∘

∘

∘

∘

∘

∘

∘

•

∘

Network decomposition

•

∘

∘

∘

∘

∘

∘

∘

∘

∘

∘

∘

∘

Get shortest paths

•

∘

∘

∘

∘

∘

∘

•

∘

∘

∘

∘

∘

Get optimal and suboptimal

             

shortest paths

•

∘

∘

∘

∘

∘

∘

∘

∘

∘

∘

∘

∘

Get all non

             

self-intersecting paths

•

∘

∘

∘

∘

∘

∘

∘

∘

∘

∘

∘

∘

Path influence quantification

•

∘

∘

∘

∘

∘

∘

∘

∘

∘

∘

∘

∘

Module manager

•

∘

∘

∘

∘

∘

∘

∘

∘

∘

∘

∘

∘

  1. The table is comparing the main functions in BiNoM with other visualization and network analysis tools. The symbol • indicates that the function is available within the tool, while ∘ indicates that the function is not available. The references for the software tools are: CellDesigner [20, 23], BioPAX2SBML [24], SyBiL [25], SBFC (Systems Biology File Converter (http://www.ebi.ac.uk/compneur-srv/sbml/converters/SBMLtoBioPax.html), biographer (http://code.google.com/p/biographer/), cySBML [26], ShortestPath (http://csresources.sourceforge.net/ShortestPath/), Glay [27], MCode [28], ModuLand [29], clusterMaker [30], NeMo [31].