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Figure 4 | BMC Systems Biology

Figure 4

From: A kinetic model for RNA-interference of focal adhesions

Figure 4

Dependence on initial conditions. Dynamics of the slip bond and catch bond model without the RNA-part and with initial conditions ACI=0.9, ACI#=0.1, RAC=1, RHO=0. Although there is only a small deviation from the Rac-IC, both models run into a steady state with a high amount of focal adhesions. Again the catch bond model leads to a higher amount of ACI# than the slip bond model. This sensitivity with respect to the initial conditions is very dependent on the parameter set. Both the sub-minute and the sub-hour timescales are visible in both plots. Parameter set PS1 was used for these plots.

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