GAP hits on positive and random datasets. Visual representation of GAP’s hits on the positive (larger set on left) and random (smaller set on right) datasets using upper percentile threshold setting. The hits in the intersection of the two yellow diamonds are those that appear in both positive and random datasets. Each circle corresponds to an interaction predicted by GAP. The size of the circles is proportional to the score of the predicted interactions (i.e., the higher the score, the larger the size). The circles’ color changes in full spectrum from purple to red as prediction scores decrease.