Skip to main content


Figure 6 | BMC Systems Biology

Figure 6

From: Probabilistic strain optimization under constraint uncertainty

Figure 6

Monte Carlo sampling based flux balance analysis (FBA) simulations identified by MCOpt for antibody production using the CHO cell model. Each panel shows a Monte Carlo distribution of FBA optimized target flux values, with the rows and columns corresponding to different caps on the number of interventions (L) and different intervention sets, respectively. Results are shown only for L = 3 and 4. The x-axis represents the maximum antibody production rate in units of nmol/106cells/day. The y-axis represents the sampled frequency of an FBA solution. The dashed lines denote the 5th and 95th percentile values. A single dashed line indicates that these two percentile values are the same.

Back to article page