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Table 1 The list of genes extracted from literary database showing association with essential hypertension

From: Construction and analysis of the protein-protein interaction network related to essential hypertension

SN

Symbol

Description

1

ACE2

angiotensin I converting enzyme 2

2

ADD1

adducin 1

3

ADIPOQ

adiponectin, C1Q and collagen domain containing

4

ADRA2B

adrenergic, alpha-2B-, receptor

5

ADRB1

adrenergic, beta-1-, receptor

6

ADRB2

adrenergic, beta-2-, receptor, surface

7

AGT

angiotensinogen

8

AGTR1

angiotensin II receptor, type 1

9

ALDH2

aldehyde dehydrogenase 2 family

10

ATP1A1

ATPase, Na+/K + transporting, alpha 1 polypeptide

11

ATP1B1

ATPase, Na+/K + transporting, beta 1 polypeptide

12

BDKRB2

bradykinin receptor B2

13

CACNA1C

calcium channel, voltage-dependent, L type, alpha 1C subunit

14

CACNA1D

calcium channel, voltage-dependent, L type, alpha 1D subunit

15

CALCA

calcitonin-related polypeptide alpha

16

CHGA

chromogranin A

17

CLCNKB

chloride channel Kb

18

CYBA

cytochrome b-245, alpha polypeptide

19

CYP11B2

cytochrome P450, family 11, subfamily B, polypeptide 2

20

CYP19A1

cytochrome P450, family 19, subfamily A, polypeptide 1

21

CYP2J2

cytochrome P450, family 2, subfamily J, polypeptide 2

22

CYP4A11

cytochrome P450, family 4, subfamily A, polypeptide 11

23

CYP4F2

cytochrome P450, family 4, subfamily F, polypeptide 2

24

EMILIN1

elastin microfibril interfacer 1

25

FABP3

fatty acid binding protein 3

26

FBN1

fibrillin 1

27

FURIN

furin (paired basic amino acid cleaving enzyme)

28

GDF15

growth differentiation factor 15

29

GNB3

guanine nucleotide binding protein, beta polypeptide 3

30

GRK4

G protein-coupled receptor kinase 4

31

GSTM3

glutathione S-transferase mu 3 (brain)

32

GUCA2B

guanylate cyclase activator 2B

33

HMOX1

heme oxygenase 1

34

HSD3B1

hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1

35

HSPA4

heat shock 70 kDa protein 4

36

IL10

interleukin 10

37

IL6

interleukin 6

38

KL

klotho

39

KLK1

kallikrein 1

40

KLKB1

kallikrein B, plasma 1

41

KNG1

kininogen 1

42

MTHFR

5,10-methylenetetrahydrofolate reductase

43

NEDD4L

neural precursor cell expressed, developmentally down-regulated 4-like

44

NOS3

nitric oxide synthase 3

45

NPPB

natriuretic peptide precursor B

46

NPR1

natriuretic peptide receptor A/guanylate cyclase A

47

NR3C2

nuclear receptor subfamily 3, group C, member 2

48

P2RY2

purinergic receptor P2Y, G-protein coupled, 2;

49

PNMT

phenylethanolamine N-methyltransferase

50

PPARG

peroxisome proliferator-activated receptor gamma

51

PSMA6

proteasome subunit, alpha type, 6

52

PTGER2

prostaglandin E receptor 2

53

PTK2B

PTK2B protein tyrosine kinase 2 beta

54

PTPN1

protein tyrosine phosphatase, non-receptor type 1

55

REN

renin

56

RNLS

renalase, FAD-dependent amine oxidase

57

SCNN1A

sodium channel, nonvoltage-gated 1 alpha

58

SCNN1B

sodium channel, nonvoltage-gated 1, beta

59

SELE

selectin E

60

SLC6A9

solute carrier family 6, member 9

61

SLC7A1

solute carrier family 7, member 1

62

SLCO1B1

solute carrier organic anion transporter family, member 1B1

63

SOD3

superoxide dismutase 3, extracellular

64

TGFB1

transforming growth factor, beta 1

65

TH

tyrosine hydroxylase

66

TNFRSF4

tumor necrosis factor receptor superfamily, member 4

67

VEGFA

vascular endothelial growth factor A

68

WNK1

WNK lysine deficient protein kinase 1

69

WNK4

WNK lysine deficient protein kinase 4